Long Term Effects For Prevacid, etc. ?

Question:

Hello: I realize this has been touched on, somewhat, in previous posts, but would like tostart a new thread devoted to this single question, please. What is the latest research regarding the taking of Prevacid (or Nexium, etc.) indefinitely ? I guess I’m bothered by all their ads that say to take only for a maximum of approx. 8 days or so, and that it is not for long term use. My general MD (and also a Gastroenteroligist I’ve seen) wants me to take it indefinitely. Their belief is that the the research on really long term effects hasn’t been done yet, or is inconclusive, and that damage to the esophogus, etc. is by far the greater danger. Any thoughts on long term effects would be most appreciated. Thanks, Bob

Response:

– Hide quoted text — Show quoted text -> Hello: > I realize this has been touched on, somewhat, in previous posts, but > would like tostart a new thread devoted to this single question, please. > What is the latest research regarding the taking of Prevacid (or Nexium, > etc.) > indefinitely ? > I guess I’m bothered by all their ads that say to take only for a maximum of > approx. > 8 days or so, and that it is not for long term use. > My general MD (and also a Gastroenteroligist I’ve seen) wants me to take it > indefinitely. > Their belief is that the the research on really long term effects hasn’t > been done yet, or is inconclusive, and that damage to the esophogus, etc. > is by far the greater danger. > Any thoughts on long term effects would be most appreciated.

There is no study that indicates that long term use of PPIs prevent esophageal cancer. In fact, just the opposite; the alkaline reflux that results from acid suppression may be more carcinogenic that the acid reflux. HMc

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