Question:
I’m not sure what happened to the original of this post. It seems to have disappeared. (If I am off topic, my apologies….otherwise, I could use some help.) Hello, folks. I have been lurking on this group for quite a while, but a recent bout of trouble with…well, my doctor isn’t really sure what is wrong at this point, even though there has been a lot of blood drawn, a couple of CT scans and an endoscopy. "We’re" looking at the other end as soon as it can be scheduled. I’m so excited I could just…well…never mind. Here’s my situation: Starting in 1982 (I was nearly 26), I began having regular bouts of heartburn. For a few years, I could control it with Tums, Rolaids, etc. I was eventually diagnosed with a hiatal hernia (recently reported to be "small"). In the past couple of years, I have been taking prescription strength Tagamet. Last winter, my family doctor put me in Prevacid, initially at 60mg per day. It worked wonders. The reason I had been in to see the doctor was because of tenderness in my abdomen. We never did determine what that was all about before it went away, but it placed us on a diagnostic path that seems to lead nowhere. My pancreatic enzymes are high (I don’t know the actual score), but there is no evidence of any problems with my pancreas. Over the past ten years, I have monitored my diet and weight in order to understand what triggers my heartburn episodes. While there are things I can point to that cause problems more than others (garlic, chocolate, alcohol), I can never predict when I am going to have real trouble until it hits. Unless, of course, I drink the least bit of brandy or eat it in foods. That will do it every time. Haven’t had it in years because of that. Oh, yeah, almost forgot. I belch a lot. Pretty melodic sometimes. It doesn’t matter if I have had anything to eat or drink in a while. In fact, one just snuck up on me and I haven’t ingested anything (except a few ounces of water with my Prevacid 2 hours ago) in 10 1/2 hours. Half the time I don’t even notice any more. I am taking 30mg of Prevacid per day and my gastroenterologist (did I get that right?) tells me "no one should have heartburn at that dose…" He, my family physician and I are equally puzzled. I am writing because I woke up at 3am with a stomach ache and couldn’t get back to sleep. Ticks me off when that happens. I have watched a number of thoughtful comments and conversations on this group. Any thoughts, observations or ideas on my situation? Anything I’ve left out of my story? TIA — Steven Kopischke Green Bay, WI
Response:
Moses here: First the disclaimer, I am not a Doc ( if you have lurked you know this) so I have my limits. My comments mixed in below with yours. – Hide quoted text — Show quoted text -> I’m not sure what happened to the original of this post. It seems to have > disappeared. (If I am off topic, my apologies….otherwise, I could use some > help.) > Hello, folks. > I have been lurking on this group for quite a while, but a recent bout of > trouble with…well, my doctor isn’t really sure what is wrong at this > point, even though there has been a lot of blood drawn, a couple of CT scans > and an endoscopy. "We’re" looking at the other end as soon as it can be > scheduled. I’m so excited I could just…well…never mind. > Here’s my situation: > Starting in 1982 (I was nearly 26), I began having regular bouts of > heartburn. For a few years, I could control it with Tums, Rolaids, etc. I > was eventually diagnosed with a hiatal hernia (recently reported to be > "small").
Yeah, small ones seem to be enough to help the LES to fail, my wife had a "small one". In the past couple of years, I have been taking prescription > strength Tagamet. Last winter, my family doctor put me in Prevacid, > initially at 60mg per day. It worked wonders. The reason I had been in > to
Well that tells you there is some dose that works. I’d say 40 milligrams of Prilosec would be more effective the 30 milligrams Prevacid, and yes 40 milligrams of Prevacid would be more likely to help also. It’s just I am not aware of the Prevacid capsule makers producing a 40 mg capsule. The comparison studies that I’ve seen the abstracts to on medline are a little stupid; in that, they compare different size doses of the drugs. Yes, I know the drug companies would say that each drug has a somewhat different activity, but the two different drug molecules are rather similiar IMHO. The 40 milligram capsule of Prilosec, the Merck company drug is about another 50 dollars a month than the 30 milligram Prevacid and the 20 milligram Prilosec. > see the doctor was because of tenderness in my abdomen. We never did > determine what that was all about before it went away, but it placed us on a > diagnostic path that seems to > lead nowhere. > My pancreatic enzymes are high (I don’t know the actual score), but there is > no evidence of any problems with my pancreas.
By this I assume you mean, the serum levels of the enzymes. This is quite worrisome. The two enzymes that my books mention are amylase and lipase. Both exist in the blood and are also excreted by the kidneys. They also are secreted in the the duodenum to digest starch and fats, respectively. Elevated levels of these enzymes can point to a number of ills. If it lasts a week or ten days, it may mean the patient has acute pancreatitis. According to the diagnostic algorithm chart, this condition is likely also marked with abdominal pain. A gall stone can be the cause of this problem. For persistent elevation of serum amylase, the chart lists three conditions, pancreatic pseudocyst, pancreatic abcess, and pancreatic ascites on this branch of the chart. On another related branch of the algorithm that includes abdominal pain, there is a chance of malignancy of the pancreas, ovary, and colon. On the "no abdominal pain branch of the algorithm chart there is listed under the "chronic elevation" is the following macroamylasemia, S-type hyperamylasemia, renal failure, and prostate disease. > Over the past ten years, I have monitored my diet and weight in order to > understand what triggers my heartburn episodes. While there are things I can > point to that cause problems more than others (garlic, chocolate, alcohol), > I can never predict when I am going to have real trouble until it hits. > Unless, of course, I drink the least bit of brandy or eat it in foods. That > will do it every time. Haven’t had it in years because of that. > Oh, yeah, almost forgot. I belch a lot. Pretty melodic sometimes. It
doesn’t Yes, the belch goes with the failed LES (lower esophageal sphinter). If you get your acid completely suppressed, you won’t notice it much. Or so I am told by a workmate with the condition. He take 40 mgs of Prilosec per day. – Hide quoted text — Show quoted text -> matter if I have had anything to eat or drink in a while. In fact, one just > snuck up on me and I haven’t ingested anything (except a few ounces of water > with my Prevacid 2 hours ago) in 10 1/2 hours. Half the time I don’t even > notice any more. > I am taking 30mg of Prevacid per day and my gastroenterologist (did I get > that right?) tells me "no one should have heartburn at that dose…" He, my > family physician and I are equally puzzled. > I am writing because I woke up at 3am with a stomach ache and couldn’t get > back to sleep. Ticks me off when that happens.
The other thing to be aware of when taking acid suppressors is that one is more vulnerable to bacteria like the toxic form of E. coli. Small children are more vulnerable to E. coli at least in part from the fact that their stomachs make less acid than an adult. Eating out is thus a bit more risky for you now. Best Wishes Moses Clarke > I have watched a number of thoughtful comments and conversations on this > group. Any thoughts, observations or ideas on my situation? Anything I’ve > left out of my story? > TIA > — > Steven Kopischke > Green Bay, WI
Share what you know. Learn what you don’t.
Response:
Well dont believe a doctor when he speaks in absolutes,, I had Heartburn at 30 mg prevacid 2 times daily. And my doctor said, he could give me as high a dose as worked, its all about finding the dosage that works for you. So ask your doctor to knock you up a notch,, maybe 45mg 2 times daily. I personally take a 30 and a 15 two times daily.. Also get checked for gastric emptying speed, maybe food sits in your stomach for a long period of time.. Ask your doctor if you might need a Motility drug in conjunction with the Proton pump inhibiting Prevacid…
Response: