Question:
How long does Celebrex take to have an effect? My doc’s trying me on it to see if it helps with my back (DDD), but I haven’t noticed any improvement. It’s been a couple of weeks now. — Katharine Shade Maxwell spamblock in action.
Response:
>How long does Celebrex take to have an effect? My doc’s trying me on it to >see if it helps with my back (DDD), but I haven’t noticed any improvement. >It’s been a couple of weeks now. >– >Katharine Shade Maxwell
Hi Katerine. Celebrex is not like certain anti depressants that can take a few weeks to get working. It should become effective in a couple of hours. Going a couple of weeks with no positive effect means it isn’t going to help you. Inform your doc of this. I’d quit taking it then, since it doesn’t seem to work, and the only things that may happen now are side effects. It’s non addicting, and doesn’t build a tolerence, and is safe to just discontinue without tapering. Just my non medical 2 cents. ~alex
Response:
Is the same thing true for Vioxx? – Hide quoted text — Show quoted text ->Celebrex is not like certain anti depressants that can take a few weeks to get >working. It should become effective in a couple of hours. Going a couple of >weeks with no positive effect means it isn’t going to help you.
Response:
Alex, My doctor told me that it would take at least 2 weeks before the medication would become effective. That is about the length of time it took to work. Sharon
– Hide quoted text — Show quoted text ->How long does Celebrex take to have an effect? My doc’s trying me on it to >see if it helps with my back (DDD), but I haven’t noticed any improvement. >It’s been a couple of weeks now. >– >Katharine Shade Maxwell > Hi Katerine. > Celebrex is not like certain anti depressants that can take a few weeks to get > working. It should become effective in a couple of hours. Going a couple of > weeks with no positive effect means it isn’t going to help you. Inform your doc > of this. > I’d quit taking it then, since it doesn’t seem to work, and the only things > that may happen now are side effects. It’s non addicting, and doesn’t build a > tolerence, and is safe to just discontinue > without tapering. Just my non medical 2 cents. > ~alex
Response:
Celebrex is an NSAID! Just a newer one, like Vioxx. the latest ulcer making, liver eating, non steroidal anti inflammatory med.! It is NOT a anti depressant! Yes, it should start to work within a week, IMO, I took it for about a week…no go…my body is different, it has had to many years of every single NSAID that has come down the pike! My entire biliary system is toasted. But, I am still alive….so…did I win the battle? Not too sure about the war, it is still going on full force! LOL Anti-inflammatories DO work to relieve the inflammation. That is the job they were developed to do, but, like all medications, you pay a price. It is up to you to decide it the price is too high. You know, that old cost=benefit conundrum! If you have not been taking NSAID’s over a long period of time, give this one a chance. It is one of the new Cox II inhibitors, if I am not wrong…Dr. Work will be along to give you the real scoop. I have found, over all these years, that there is not a opiate in the world that will take ALL the pain away. Of course, you can titrate them up until you are in much less pain, but…your brain goes into fog-ville..big time. It is always a trade off, isn’t it? After all these years I have finally learned to use ALL the tricks in my little bag. Some laugh at some of them or all of them, but I am living proof that using other modalities work! It takes time, patience, preparing, and most of all a very open mind to get there. But..it works for a lot of people! My friend was dx’d with Pancreatic Cancer, had a Full Whipple done two years ago as of last Dec. 14! Went through 24/7 of chemo, full course of radiation. She is cancer free…..for now…BUT, during all the trauma of going through the above she used alliterative medicine with her Western medicine. She has a herbalist, an acuputurist, uses, as I do, Imaging, Breathing technics, biofeedback, diet. We eat very little red meat. But, back to your question…( I am so wordy! Geesh, sorry!), give the Celebrex a chance, but look into some other methods of treatment too. Sincerely, Jo – Hide quoted text — Show quoted text – >Alex, >My doctor told me that it would take at least 2 weeks before the medication >would become effective. That is about the length of time it took to work. >Sharon > >How long does Celebrex take to have an effect? My doc’s trying me on it >to > >see if it helps with my back (DDD), but I haven’t noticed any >improvement. > >It’s been a couple of weeks now. > >– > >Katharine Shade Maxwell > Hi Katerine. > Celebrex is not like certain anti depressants that can take a few weeks to >get > working. It should become effective in a couple of hours. Going a couple >of > weeks with no positive effect means it isn’t going to help you. Inform >your doc > of this. > I’d quit taking it then, since it doesn’t seem to work, and the only >things > that may happen now are side effects. It’s non addicting, and doesn’t >build a > tolerence, and is safe to just discontinue > without tapering. Just my non medical 2 cents. > ~alex
Response:
>Celebrex is an NSAID! Just a newer one, like Vioxx. the latest >ulcer making, liver eating, non steroidal anti inflammatory med.! >It is NOT a anti depressant!
Noone said it was an anti-depressant..someone said that it wasnt LIKE on in the fact that it can take weeks for improvement…Celebrex/Vioxx usually work within a week, sometimes less. Oh, and technically it is a COX-2 inhibitor…and for alot of people that couldnt take NSAIDS before, can take this. I am one of them. It targets the COX 2 enzyme, which is supposed to make things like ulcers a bit more rare than with conventional NSAIDS. Nikki "… lost in the darkness of my own circumstance, criticizing echoes leaving me awake in the night… the barrier and blockades that keep me safe and in control while I pretend that I am okay… "
Response:
> Is the same thing true for Vioxx? >Celebrex is not like certain anti depressants that can take a few weeks to get >working. It should become effective in a couple of hours. Going a couple of >weeks with no positive effect means it isn’t going to help you.
Yes. Jon Miller
Response:
> >Celebrex is an NSAID! Just a newer one, like Vioxx. the latest >ulcer making, liver eating, non steroidal anti inflammatory med.! >It is NOT a anti depressant! > Noone said it was an anti-depressant..someone said that it wasnt LIKE on in the > fact that it can take weeks for improvement…Celebrex/Vioxx usually work > within a week, sometimes less. Oh, and technically it is a COX-2 > inhibitor…and for alot of people that couldnt take NSAIDS before, can take > this. I am one of them. It targets the COX 2 enzyme, which is supposed to make > things like ulcers a bit more rare than with conventional NSAIDS.
It’s supposed to make them a lot more rare. It’s supposed to target the COX-2 enzyme (pain receptor) and leave the COX-1 enzyme (which tells the stomach lining to produce more acid or less protective coating, I forget which) alone. My recollection (you have to look it up for yourself if you need to be sure, try Medline) is that users don’t have significantly fewer digestive system problems. Given the cost, you probably shouldn’t switch to a COX-2 inhibitor unless you have problems with the older NSAIDs (or free drugs with your insurance, haha!). Jon Miller
Response:
Thanks, Nikki, you are right, of course…I just didn’t pay enough attention to the post. Very bad habit, I am working on it!! :) Jo
– Hide quoted text — Show quoted text ->Celebrex is an NSAID! Just a newer one, like Vioxx. the latest >ulcer making, liver eating, non steroidal anti inflammatory med.! >It is NOT a anti depressant! >Noone said it was an anti-depressant..someone said that it wasnt LIKE on in the >fact that it can take weeks for improvement…Celebrex/Vioxx usually work >within a week, sometimes less. Oh, and technically it is a COX-2 >inhibitor…and for alot of people that couldnt take NSAIDS before, can take >this. I am one of them. It targets the COX 2 enzyme, which is supposed to make >things like ulcers a bit more rare than with conventional NSAIDS. >Nikki >"… lost in the darkness of my own circumstance, criticizing echoes leaving me >awake in the night… the barrier and blockades that keep me safe and in >control while I pretend that I am okay… "
Response:
I have a friend that I joke with that Celebrex is the "wonder drug". docs love to give out samples of this and I have tried it and have found that it does not work. No matter how long I tried it. It had no effect on me. Hope that you have better luck… karra
– Hide quoted text — Show quoted text ->How long does Celebrex take to have an effect? My doc’s trying me on it to >see if it helps with my back (DDD), but I haven’t noticed any improvement. >It’s been a couple of weeks now. >– >Katharine Shade Maxwell >spamblock in action.
Response:
> I have a friend that I joke with that Celebrex is the "wonder drug". docs > love to give out samples of this and I have tried it and have found that it > does not work. No matter how long I tried it. It had no effect on me. Hope > that you have better luck… > karra
Kara , It may not work , but at least it won’t hurt your stomach . Peace , Richard
Response:
– Hide quoted text — Show quoted text -> I have a friend that I joke with that Celebrex is the "wonder drug". docs > love to give out samples of this and I have tried it and have found that > it > does not work. No matter how long I tried it. It had no effect on me. Hope > that you have better luck… > karra > Kara , > It may not work , but at least it won’t hurt your stomach . > Peace , > Richard
It hurts mine Richard — so does the Vioxx.
Response:
> I have a friend that I joke with that Celebrex is the "wonder drug". docs > love to give out samples of this and I have tried it and have found that it > does not work. No matter how long I tried it. It had no effect on me. Hope > that you have better luck… > karra
Karra, It is a shame that Celebrex didn’t work for you. I have been taking it for awhile now and am doing pretty good, so I thought maybe I didn’t need it. I stopped taking it and in a few days I felt arthritis pain in places I didn’t know I had it. It hasn’t stopped the pain entirely, but it sure helps me. So far, I haven’t had any stomach problems. I guess I have just been lucky. Sharon
Response:
Richard, me too. Major problems with Celebrex!! I’m back on the ulcer watch, taking those ridiculously high drugs, all because my stomach. HA, Jo BTW Ruada, sorry you had trouble too. Wouldn’t it be nice if we could really Find a drug that worked without playing major havoc with the rest of our system? Jo – Hide quoted text — Show quoted text -> > I have a friend that I joke with that Celebrex is the "wonder >drug". docs > > love to give out samples of this and I have tried it and have >found that > it > > does not work. No matter how long I tried it. It had no effect on >me. Hope > > that you have better luck… > > karra > Kara , > It may not work , but at least it won’t hurt your stomach . > Peace , > Richard >It hurts mine Richard — so does the Vioxx.
Response:
> Newsgroups: alt.support.chronic-pain > Richard, me too. Major problems with Celebrex!! I’m back on the > ulcer watch, taking those ridiculously high drugs, all because my > stomach. HA, Jo > BTW Ruada, sorry you had trouble too. Wouldn’t it be nice if we > could really Find a drug that worked without playing major havoc > with the rest of our system? Jo
I don’t have stomach problems from Celebrex. If I had to give up one or the other I’d give up the morphine first! The Celebrex does cause my ankles to swell so I have to take extra diuretics for it. But it really makes a difference with pain. On the other hand I also don’t need anything for "opiate bowel" either! – Hide quoted text — Show quoted text ->> > I have a friend that I joke with that Celebrex is the "wonder >drug". docs >> > love to give out samples of this and I have tried it and have >found that >> it >> > does not work. No matter how long I tried it. It had no effect > on >me. Hope >> > that you have better luck… >> > karra >> Kara , >> It may not work , but at least it won’t hurt your stomach . >> Peace , >> Richard >It hurts mine Richard — so does the Vioxx.
– *** http://medstuff.ftn.org – for the sake of your health *** *** http://www.ftn.org Fight the creatures of The Night ****
Response:
Alex, I have tried both celebrex and vioxx. They don’t do anything beneficial for me so I have resumed taking 1000 mg Relefen. I feel some relief from joint swelling but not enough. I tried taking the Relefen in the morning and found that this causes terrible heartburn all day. I take it at night now and don’t suffer from heartburn and sleep much better. I was wondering if you know of any other NSAID’s that might work? My last appointment on Jan 30th revealed that there is significant damage to my knees and joint replacement may be viable in the near future. My lower back was the main reasons for seeing this DR and the pain clinic. I guess this all goes along with DDD and DJD. I was not ready for these diseases to affect me so rapidly. I am approaching 40 and was a welder/fabricator/millwright for many years and blame the knee damage on the goofy positions I placed myself in, only to get the job done. I thought the many years of martial arts would’ve slowed down the process, maybe it did. Maybe the added stress to my body made it weaker instead, who knows? I don’t know why I am dumping this shit on you so forgive the intrusion if it bothers you. I’m just looking for an anti-inflammatory that might give me some more time. The only other drug of this king that I have tried is Naproxen and I think it is pretty much the same as the Relefen. Best to you and your family. Rob H
– Hide quoted text — Show quoted text -> Just an FYI. > In today’s USA Today (Tues, Feb 6, 2001) > there is a cover artlcle in the LIFE section. > For some strange reason, this artcle is not included in the USAToday.com > website: > http://www.usatoday.com > I was gonna post a link, but seeing that the artcle isn’t there, I guess it’s > no go. > Basically, it talks about Celebrex and Vioxx > and how their actions haven’t been proven to be any more effective than > aspirin, or ibuprofen. > It also states that these 2 NSAIDS and Cox-2 inhibitors may make GI problems > less severe than their counterpar NSAIDS like relefen. > Also, the makers are going before the FDA tomorrow to see if they can take away > the warnings that other NSAID drugs must contain about the strong possibility > of GI problems such as ulcers, bleeding and perferation. > It also states that sales of Vioxx and Celebrex combined, have topped $3.2 > billion from Jan-Nov 2000. > Celebrex sales were $1.9 billion in this period (up 55% from the previous > year)) > while Vioxx sales were $1.2 billion (up 376% from the previous year) > They say that sales of these 2 products still have much more room to increase, > especially if the FDA approves removal of the GI warnings that both must > include. > Just thought some of you may be interested > in this info. > ~alex
Response:
Rob, I agree with you, the cost of the Celebrex and Vioxx is outrageous and they do not do much to relive the pain anyway, do they? You spoke of seeing a joint replacement down the road. I hope that you will consider it! I don’t know what the stats are for someone as young as you but I am here to tell you that getting my rt. knee replacement is Sept., even with the slowdown in healing because of my diabetes and auto-immune problems. was worth every single pain the rehab cost! I would never tell you that it wasn’t hard to go thru, the pain the first days is at a 14+, and the first few days were hell, BUT, I was walking down the hall within days and up and down stairs, (just like a normal person LOL) within a week! I have absolutely NO pain in the joint! My problems with the healing process notwithstanding, I am going to see if they will do the other knee, maybe next year! You can only go so long on any NSAID before you develop gastric and biliary problems. That is just the facts! They all, even the Cox 2’s cause those problems. It frightens me that so many people are wolfing down all those OTC NSAID’s thinking they are so safe! When we all know that they are dangerous! Jo – Hide quoted text — Show quoted text – >Alex, I have tried both celebrex and vioxx. They don’t do anything >beneficial for me so I have resumed taking 1000 mg Relefen. I feel some >relief from joint swelling but not enough. I tried taking the Relefen in >the morning and found that this causes terrible heartburn all day. I take >it at night now and don’t suffer from heartburn and sleep much better. I >was wondering if you know of any other NSAID’s that might work? My last >appointment on Jan 30th revealed that there is significant damage to my >knees and joint replacement may be viable in the near future. My lower back >was the main reasons for seeing this DR and the pain clinic. I guess this >all goes along with DDD and DJD. I was not ready for these diseases to >affect me so rapidly. I am approaching 40 and was a >welder/fabricator/millwright for many years and blame the knee damage on the >goofy positions I placed myself in, only to get the job done. I thought the >many years of martial arts would’ve slowed down the process, maybe it did. >Maybe the added stress to my body made it weaker instead, who knows? I >don’t know why I am dumping this shit on you so forgive the intrusion if it >bothers you. I’m just looking for an anti-inflammatory that might give me >some more time. The only other drug of this king that I have tried is >Naproxen and I think it is pretty much the same as the Relefen. >Best to you and your family. >Rob H > Just an FYI. > In today’s USA Today (Tues, Feb 6, 2001) > there is a cover artlcle in the LIFE section. > For some strange reason, this artcle is not included in the USAToday.com > website: > http://www.usatoday.com > I was gonna post a link, but seeing that the artcle isn’t there, I guess >it’s > no go. > Basically, it talks about Celebrex and Vioxx > and how their actions haven’t been proven to be any more effective than > aspirin, or ibuprofen. > It also states that these 2 NSAIDS and Cox-2 inhibitors may make GI >problems > less severe than their counterpar NSAIDS like relefen. > Also, the makers are going before the FDA tomorrow to see if they can take >away > the warnings that other NSAID drugs must contain about the strong >possibility > of GI problems such as ulcers, bleeding and perferation. > It also states that sales of Vioxx and Celebrex combined, have topped $3.2 > billion from Jan-Nov 2000. > Celebrex sales were $1.9 billion in this period (up 55% from the previous > year)) > while Vioxx sales were $1.2 billion (up 376% from the previous year) > They say that sales of these 2 products still have much more room to >increase, > especially if the FDA approves removal of the GI warnings that both must > include. > Just thought some of you may be interested > in this info. > ~alex
Response:
Jo, I really hope that the knee thing can be put off for a long while. I have no doubt that the replacement would be successful but when it comes to my knees, I’m a big baby! Even the thought of being given the cortisone and other injections causes my teeth to itch! I can move my knee caps all over the place and sometimes without warning, they lock and down I go. I usually have to climb my cane to get vertical again. The pain is so severe sometimes I can’t keep my legs still, trying to find the sweet spot that will alleviate the pounding. I have had some major surgery before and have never been afraid but find myself scared stupid for some reason. I realize intellectually that replacements would be less painful than going through the paces to put off surgery but it hasn’t really hit home yet. What was the worst scenario the DR’s gave you to think about and the odds on successful surgery? Either way the worst being not able to walk. I know I can’t keep eating NSAID’s for the rest of my life. I don’t think they are doing anything special now, just giving me heartburn. I eat 300 mg’s of MS Contin now and this isn’t touching the knee pain, this is a major factor contributing to my fear, I think! My back pain is being fairly well taken care of though and that is questionable at times. I have a fairly high tolerance to pain and fear the day when I just can’t take anymore. Thanks for the shoulder to cry on and I wish you the best in clearing up that nasty infection. I think maybe you should retire from the caregiver position and pass the torch to someone else. You must take care of yourself so you can be their for her. In the least, get some kind of outside help to assist you and your sister, three days a week. Easier said than done but you are a resourceful lady and if anyone can pull this off, you can! Be well!! Rob H
– Hide quoted text — Show quoted text -> Rob, I agree with you, the cost of the Celebrex and Vioxx is > outrageous and they do not do much to relive the pain anyway, do > they? > You spoke of seeing a joint replacement down the road. I hope that > you will consider it! I don’t know what the stats are for someone > as young as you but I am here to tell you that getting my rt. knee > replacement is Sept., even with the slowdown in healing because of > my diabetes and auto-immune problems. was worth every single pain > the rehab cost! > I would never tell you that it wasn’t hard to go thru, the pain the > first days is at a 14+, and the first few days were hell, BUT, I was > walking down the hall within days and up and down stairs, (just like > a normal person LOL) within a week! I have absolutely NO pain in > the joint! My problems with the healing process notwithstanding, I > am going to see if they will do the other knee, maybe next year! > You can only go so long on any NSAID before you develop gastric and > biliary problems. That is just the facts! They all, even the Cox > 2’s cause those problems. It frightens me that so many people are > wolfing down all those OTC NSAID’s thinking they are so safe! When > we all know that they are dangerous! > Jo
<SNIP>
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